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白细胞介素-15(IL-15)由单核细胞、巨噬细胞、树突细胞和上皮细胞等多种细胞分泌形成。IL-15可促进自然杀伤(NK)细胞、自然杀伤T(NKT)细胞和CD8+记忆T细胞的激活和扩增,与IL-2不同的是,它不会影响CD4+调节T细胞(Treg),也不会诱导活化诱导的细胞死亡(AICD)。IL-15信号传递可激活多种途径,进而影响细胞增殖、抗凋亡存活和细胞毒效应功能。 IL-15 Bioassay, Propagation Model是一种基于生物发光细胞的测定法,旨在使用STAT-5响应元素进行读取,以测定IL-15的刺激或抑制作用。以细胞传代模型形式提供IL-15生物测定细胞,包括可被解冻、繁殖和形成细胞库作长期使用的冻存细胞(也可以方便解冻使用的形式提供;产品目录编号JA2011、JA2015)。
询价IKKε Kinase Enzyme System Easily Screen and Profile IKKε Kinase Inhibitors Includes kinase, substrate and reaction buffer Use with ADP-Glo™ Assay for bioluminescent detection of kinase activity
询价IKKε Kinase Enzyme System Easily Screen and Profile IKKε Kinase Inhibitors Includes kinase, substrate and reaction buffer Use with ADP-Glo™ Assay for bioluminescent detection of kinase activity
询价IKKβ Kinase Enzyme System Easily Screen and Profile IKKβ Kinase Inhibitors Includes kinase, substrate and reaction buffer Use with ADP-Glo™ Assay for bioluminescent detection of kinase activity
询价IKKβ Kinase Enzyme System Easily Screen and Profile IKKβ Kinase Inhibitors Includes kinase, substrate and reaction buffer Use with ADP-Glo™ Assay for bioluminescent detection of kinase activity
询价IKKα Kinase Enzyme System Easily Screen and Profile IKKα Kinase Inhibitors Includes kinase, substrate and reaction buffer Use with ADP-Glo™ Assay for bioluminescent detection of kinase activity
询价IKKα Kinase Enzyme System Easily Screen and Profile IKKα Kinase Inhibitors Includes kinase, substrate and reaction buffer Use with ADP-Glo™ Assay for bioluminescent detection of kinase activity
询价Kinase Fusion Vector for NanoBRET™ Target Engagement Transfection-ready DNA to express full-length IGF1R kinase fused to NanoLuc® Luciferase Measures kinase target engagement in live cells Use with NanoBRET™ TE Intracellular Kinase Assay, Adherent Format protocol
询价IGF1R Kinase Enzyme System Easily Screen and Profile IGF1R Kinase Inhibitors Includes kinase, substrate and reaction buffer Use with ADP-Glo™ Assay for bioluminescent detection of kinase activity
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